Since there are over 100,000 stars in just one galaxy, I don't think we'd need to visit other galaxies. Besides, Will Wright said that there was just the one in his Gaming Steve interview. I think it was the second one.
Yep, that was a pretty definite no. Besides, the distances of the closest galaxies are gigantic. Andromeda is 2 million light years away. If this dash - (1mm, lets say) was a light year, and you were to walk from here to Andromeda, you'd have to walk 2.5 Kilometers, and the Milky way in this picture is only about 80-100 Meters in Diameter, while the Andromeda is 220 meters in Diameter. The Sun in this picture would be about the size of a medium sized atom (1.47e-11 meters). Earth may as well be a quantum singularity in the Big Picture of just the local Group.
Oh, and there are 100,000,000,000 stars in the Milky way; 200,000,000,000 stars in Andromeda. The Spore galaxy would be a pipsqueak, even compared to the small dwarf galaxies whose star counts still range in the millions to billions.